Symbol: Name: ID: |
CARD9 caspase recruitment domain family, member 9 GFS:5507 |
Gene name: | CARD9 |
Chromosome: | 9q34 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2685628 | Rat Genome Database ID: | RGD:708370 |
HGNC ID: | HGNC:16391 | RefSeq IDs: | NM_052813 |
Entrez Gene ID: | 64170 | Ensembl Gene ID: | ENSG00000187796 |
VEGA IDs: | OTTHUMG00000020925 | UniProt ID: | Q9H257 |
UCSC ID: | uc004chg.3 | OMIM ID: | 607212 |
Pubmed: | PMID11053425 | ||
CCDS IDs: | CCDSCCDS6997.1 CCDS CCDS48057.1 |
Caspase recruitment domain-containing protein 9 is an adaptor protein that in humans is encoded by the CARD9 gene.
The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined. [provided by RefSeq, Jul 2008].
Function: Activates NF-kappa-B via BCL10.
Products for CARD9 gene
Catalog | Product Name | Application | Company |
GFS:E05507 | caspase recruitment domain family, member 9; ELISA kit | ELISA | n/a |
GFS:A05507 | caspase recruitment domain family, member 9; Anti | ANTIBODIES | n/a |
GFS:P05507 | caspase recruitment domain family, member 9; Protien | Protien | n/a |