| Symbol: Name: ID: |
CARD10 caspase recruitment domain family, member 10 GFS:5535 |
| Gene name: | CARD10 |
| Chromosome: | 22q13.1 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | CARMA3, BIMP1 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:2146012 | Rat Genome Database ID: | RGD:1304949 |
| HGNC ID: | HGNC:16422 | RefSeq IDs: | NM_014550 |
| Entrez Gene ID: | 29775 | Ensembl Gene ID: | ENSG00000100065 |
| VEGA IDs: | OTTHUMG00000150592 | UniProt ID: | Q9BWT7 |
| UCSC ID: | uc003asx.1 | OMIM ID: | 607209 |
| Pubmed: | PMID11259443 PMID 11356195 | ||
| CCDS IDs: | CCDSCCDS13948.1 | ||
Caspase recruitment domain-containing protein 10 is an enzyme that in humans is encoded by the CARD10 gene.
The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM, Mar 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Activates NF-kappa-B via BCL10 and IKK.
Products for CARD10 gene
| Catalog | Product Name | Application | Company |
| GFS:E05535 | caspase recruitment domain family, member 10; ELISA kit | ELISA | n/a |
| GFS:A05535 | caspase recruitment domain family, member 10; Anti | ANTIBODIES | n/a |
| GFS:P05535 | caspase recruitment domain family, member 10; Protien | Protien | n/a |
