Symbol: Name: ID: |
TBX4 T-box 4 GFS:1454 |
Gene name: | TBX4 |
Chromosome: | 17q21-q22 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:102556 | Rat Genome Database ID: | RGD:1309057 |
HGNC ID: | HGNC:11603 | RefSeq IDs: | NM_018488 |
Entrez Gene ID: | 9496 | Ensembl Gene ID: | ENSG00000121075 |
VEGA IDs: | UniProt ID: | P57082 | |
UCSC ID: | uc002izi.2 | OMIM ID: | 601719 |
Pubmed: | PMID10945475 | ||
CCDS IDs: | CCDSCCDS11629.1 |
The TBX4 gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human homolog of mouse Tbx4, which is closely linked to Tbx2 on mouse chromosome 11. Similarly this gene, like TBX2, maps to human chromosome 17. Expression studies in mouse and chicken show that Tbx4 is expressed in developing hindlimb, but not in forelimb buds, suggesting a role for this gene in regulating limb development and specification of limb identity. [provided by RefSeq].
Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation.
Products for TBX4 gene
Catalog | Product Name | Application | Company |
GFS:E01454 | T-box 4; ELISA kit | ELISA | n/a |
GFS:A01454 | T-box 4; Anti | ANTIBODIES | n/a |
GFS:P01454 | T-box 4; Protien | Protien | n/a |