Symbol: Name: ID: |
TBXAS1 thromboxane A synthase 1 (platelet) GFS:1459 |
Gene name: | TBXAS1 |
Chromosome: | 7q34-q35 |
Previous Symbols: | |
Previous Names: | thromboxane A synthase 1 (platelet, cytochrome P450, subfamily V) |
Aliases: | CYP5, CYP5A1, THAS, TXS, TXAS, TS |
Name Aliases: | cytochrome P450, family 5, subfamily A, polypeptide 1 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98497 | Rat Genome Database ID: | RGD:3826 |
HGNC ID: | HGNC:11609 | RefSeq IDs: | NM_001061 |
Entrez Gene ID: | 6916 | Ensembl Gene ID: | ENSG00000059377 |
VEGA IDs: | OTTHUMG00000157302 | UniProt ID: | P24557 |
UCSC ID: | uc003vvi.2 | OMIM ID: | 274180 |
Pubmed: | PMID1714723 PMID 8964509 | ||
CCDS IDs: | CCDSCCDS5855.1 CCDS CCDS5856.1 |
Thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A), also known as TBXAS1, is an enzyme that, in humans, is encoded by the TBXAS1 gene. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Products for TBXAS1 gene
Catalog | Product Name | Application | Company |
GFS:E01459 | thromboxane A synthase 1 (platelet); ELISA kit | ELISA | n/a |
GFS:A01459 | thromboxane A synthase 1 (platelet); Anti | ANTIBODIES | n/a |
GFS:P01459 | thromboxane A synthase 1 (platelet); Protien | Protien | n/a |