Symbol: Name: ID: |
TBX3 T-box 3 GFS:1453 |
Gene name: | TBX3 |
Chromosome: | 12q24.1 |
Previous Symbols: | UMS |
Previous Names: | ulnar mammary syndrome |
Aliases: | TBX3-ISO, XHL |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98495 | Rat Genome Database ID: | RGD:735203 |
HGNC ID: | HGNC:11602 | RefSeq IDs: | NM_005996 |
Entrez Gene ID: | 6926 | Ensembl Gene ID: | ENSG00000135111 |
VEGA IDs: | UniProt ID: | O15119 | |
UCSC ID: | uc001tvt.1 | OMIM ID: | 601621 |
Pubmed: | PMID8988164 | ||
CCDS IDs: | CCDSCCDS9175.1 CCDS CCDS9176.1 |
T-box transcription factor TBX3 is a protein that in humans is encoded by the TBX3 gene. This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined. [provided by RefSeq].
Function: Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation.
Products for TBX3 gene
Catalog | Product Name | Application | Company |
GFS:E01453 | T-box 3; ELISA kit | ELISA | n/a |
GFS:A01453 | T-box 3; Anti | ANTIBODIES | n/a |
GFS:P01453 | T-box 3; Protien | Protien | n/a |