Symbol: Name: ID: |
CDC42EP5 CDC42 effector protein (Rho GTPase binding) 5 GFS:6472 |
Gene name: | CDC42EP5 |
Chromosome: | 19q13.42 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CEP5, Borg3 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1929745 | Rat Genome Database ID: | RGD:1308382 |
HGNC ID: | HGNC:17408 | RefSeq IDs: | NM_145057 |
Entrez Gene ID: | 148170 | Ensembl Gene ID: | ENSG00000167617 |
VEGA IDs: | OTTHUMG00000065699 | UniProt ID: | Q6NZY7 |
UCSC ID: | uc002qfz.1 | OMIM ID: | 609171 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS12896.1 |
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. The specific function of this protein has not yet been determined. [provided by RefSeq, Jul 2008].
Function: Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Inhibits MAPK8 independently of CDC42 binding. Controls septin organization and this effect is negatively regulated by CDC42 (By similarity)
Products for CDC42EP5 gene
Catalog | Product Name | Application | Company |
GFS:E06472 | CDC42 effector protein (Rho GTPase binding) 5; ELISA kit | ELISA | n/a |
GFS:A06472 | CDC42 effector protein (Rho GTPase binding) 5; Anti | ANTIBODIES | n/a |
GFS:P06472 | CDC42 effector protein (Rho GTPase binding) 5; Protien | Protien | n/a |