| Symbol: Name: ID: |
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) GFS:6457 |
| Gene name: | CDC42BPB |
| Chromosome: | 14q32.32 |
| Previous Symbols: | |
| Previous Names: | CDC42-binding protein kinase beta (DMPK-like) |
| Aliases: | MRCKB, KIAA1124 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:2136459 | Rat Genome Database ID: | RGD:621753 |
| HGNC ID: | HGNC:1738 | RefSeq IDs: | NM_006035 |
| Entrez Gene ID: | 9578 | Ensembl Gene ID: | ENSG00000198752 |
| VEGA IDs: | OTTHUMG00000029158 | UniProt ID: | Q9Y5S2 |
| UCSC ID: | uc001ymi.1 | OMIM ID: | |
| Pubmed: | PMID10198171 | ||
| CCDS IDs: | CCDSCCDS9978.1 | ||
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization. [provided by RefSeq, Jul 2008].
Function: May act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation (By similarity).
Products for CDC42BPB gene
| Catalog | Product Name | Application | Company |
| GFS:E06457 | CDC42 binding protein kinase beta (DMPK-like); ELISA kit | ELISA | n/a |
| GFS:A06457 | CDC42 binding protein kinase beta (DMPK-like); Anti | ANTIBODIES | n/a |
| GFS:P06457 | CDC42 binding protein kinase beta (DMPK-like); Protien | Protien | n/a |
