| Symbol: Name: ID: |
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) GFS:6449 |
| Gene name: | CDC42BPA |
| Chromosome: | 1q42.11 |
| Previous Symbols: | |
| Previous Names: | CDC42-binding protein kinase alpha (DMPK-like) |
| Aliases: | MRCKA, PK428, FLJ23347, KIAA0451, MRCK |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:2441841 | Rat Genome Database ID: | RGD:621406 |
| HGNC ID: | HGNC:1737 | RefSeq IDs: | NM_003607 |
| Entrez Gene ID: | 8476 | Ensembl Gene ID: | ENSG00000143776 |
| VEGA IDs: | OTTHUMG00000037618 | UniProt ID: | Q5VT25 |
| UCSC ID: | uc001hqr.2 | OMIM ID: | 603412 |
| Pubmed: | |||
| CCDS IDs: | CCDSCCDS1558.1 CCDS CCDS1559.1 | ||
Serine/threonine-protein kinase MRCK alpha is an enzyme that in humans is encoded by the CDC42BPA gene.
The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. [provided by RefSeq, Jul 2008].
Function: May act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation.
Products for CDC42BPA gene
| Catalog | Product Name | Application | Company |
| GFS:E06449 | CDC42 binding protein kinase alpha (DMPK-like); ELISA kit | ELISA | n/a |
| GFS:A06449 | CDC42 binding protein kinase alpha (DMPK-like); Anti | ANTIBODIES | n/a |
| GFS:P06449 | CDC42 binding protein kinase alpha (DMPK-like); Protien | Protien | n/a |
