Symbol: Name: ID: |
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) GFS:3052 |
Gene name: | VPS4A |
Chromosome: | 16q23.1 |
Previous Symbols: | |
Previous Names: | vacuolar protein sorting 4A (yeast homolog), "vacuolar protein sorting 4A (yeast)" |
Aliases: | VPS4, VPS4-1, FLJ22197, SKD2, SKD1, SKD1A |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1890520 | Rat Genome Database ID: | RGD:628810 |
HGNC ID: | HGNC:13488 | RefSeq IDs: | NM_013245 |
Entrez Gene ID: | 27183 | Ensembl Gene ID: | ENSG00000132612 |
VEGA IDs: | OTTHUMG00000073636 | UniProt ID: | Q9UN37 |
UCSC ID: | uc002eww.2 | OMIM ID: | 609982 |
Pubmed: | PMID10637304 PMID 11563910 | ||
CCDS IDs: | CCDSCCDS45517.1 |
Vacuolar protein sorting-associated protein 4A is a protein that in humans is encoded by the VPS4A gene.
The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16; the gene for the other resides on chromosome 18. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for VPS4A gene
Catalog | Product Name | Application | Company |
GFS:E03052 | vacuolar protein sorting 4 homolog A (S. cerevisiae); ELISA kit | ELISA | n/a |
GFS:A03052 | vacuolar protein sorting 4 homolog A (S. cerevisiae); Anti | ANTIBODIES | n/a |
GFS:P03052 | vacuolar protein sorting 4 homolog A (S. cerevisiae); Protien | Protien | n/a |