Symbol: Name: ID: |
VPS33B vacuolar protein sorting 33 homolog B (yeast) GFS:2483 |
Gene name: | VPS33B |
Chromosome: | 15q26.1 |
Previous Symbols: | |
Previous Names: | vacuolar protein sorting 33B (yeast homolog) |
Aliases: | FLJ14848 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2446237 | Rat Genome Database ID: | RGD:620644 |
HGNC ID: | HGNC:12712 | RefSeq IDs: | NM_018668 |
Entrez Gene ID: | 26276 | Ensembl Gene ID: | ENSG00000184056 |
VEGA IDs: | OTTHUMG00000149835 | UniProt ID: | Q9H267 |
UCSC ID: | uc002bqp.1 | OMIM ID: | 608552 |
Pubmed: | PMID8996080 | ||
CCDS IDs: | CCDSCCDS10369.1 |
Vacuolar protein sorting-associated protein 33B is a protein that in humans is encoded by the VPS33B gene.
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages.
Products for VPS33B gene
Catalog | Product Name | Application | Company |
GFS:E02483 | vacuolar protein sorting 33 homolog B (yeast); ELISA kit | ELISA | n/a |
GFS:A02483 | vacuolar protein sorting 33 homolog B (yeast); Anti | ANTIBODIES | n/a |
GFS:P02483 | vacuolar protein sorting 33 homolog B (yeast); Protien | Protien | n/a |