Symbol: Name: ID: |
TH tyrosine hydroxylase GFS:1600 |
Gene name: | TH |
Chromosome: | 11p15.5 |
Previous Symbols: | |
Previous Names: | |
Aliases: | DYT5b |
Name Aliases: | tyrosine 3-monooxygenase |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98735 | Rat Genome Database ID: | RGD:3853 |
HGNC ID: | HGNC:11782 | RefSeq IDs: | NM_000360 |
Entrez Gene ID: | 7054 | Ensembl Gene ID: | ENSG00000180176 |
VEGA IDs: | OTTHUMG00000009559 | UniProt ID: | P07101 |
UCSC ID: | uc001lvp.2 | OMIM ID: | 191290 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS7730.1 CCDS CCDS7731.1 CCDS CCDS31338.1 |
Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to dihydroxyphenylalanine (DOPA). The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq].
Function: Plays an important role in the physiology of adrenergic neurons.
Products for TH gene
Catalog | Product Name | Application | Company |
GFS:E01600 | tyrosine hydroxylase; ELISA kit | ELISA | n/a |
GFS:A01600 | tyrosine hydroxylase; Anti | ANTIBODIES | n/a |
GFS:P01600 | tyrosine hydroxylase; Protien | Protien | n/a |