Symbol: Name: ID: |
THRSP thyroid hormone responsive GFS:1616 |
Gene name: | THRSP |
Chromosome: | 11q13.5 |
Previous Symbols: | LPGP1 |
Previous Names: | thyroid hormone responsive SPOT14 (rat) homolog, "lipogenic protein 1" |
Aliases: | SPOT14, Lpgp, S14 |
Name Aliases: | SPOT14 homolog (rat) |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:109126 | Rat Genome Database ID: | RGD:3859 |
HGNC ID: | HGNC:11800 | RefSeq IDs: | NM_003251 |
Entrez Gene ID: | 7069 | Ensembl Gene ID: | ENSG00000151365 |
VEGA IDs: | UniProt ID: | Q92748 | |
UCSC ID: | uc001oyx.2 | OMIM ID: | 601926 |
Pubmed: | PMID9003802 | ||
CCDS IDs: | CCDSCCDS8256.1 |
Thyroid hormone-inducible hepatic protein is a protein that in humans is encoded by the THRSP gene. The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to liver and adipose tissue and is controlled by nutritional and hormonal factors. This gene has been shown to be expressed in liver and adipocytes, particularly in lipomatous modules. It is also found to be expressed in lipogenic breast cancers, which suggests a role in controlling tumor lipid metabolism. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.
Products for THRSP gene
Catalog | Product Name | Application | Company |
GFS:E01616 | thyroid hormone responsive; ELISA kit | ELISA | n/a |
GFS:A01616 | thyroid hormone responsive; Anti | ANTIBODIES | n/a |
GFS:P01616 | thyroid hormone responsive; Protien | Protien | n/a |