Symbol: Name: ID: |
TGFB1I1 transforming growth factor beta 1 induced transcript 1 GFS:1585 |
Gene name: | TGFB1I1 |
Chromosome: | 16p11 |
Previous Symbols: | |
Previous Names: | |
Aliases: | Hic-5, TSC-5, ARA55, HIC-5 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:102784 | Rat Genome Database ID: | RGD:620173 |
HGNC ID: | HGNC:11767 | RefSeq IDs: | NM_001042454 |
Entrez Gene ID: | 7041 | Ensembl Gene ID: | ENSG00000140682 |
VEGA IDs: | OTTHUMG00000132467 | UniProt ID: | O43294 |
UCSC ID: | uc002ecd.1 | OMIM ID: | 602353 |
Pubmed: | PMID9422762 PMID 10075738 | ||
CCDS IDs: | CCDSCCDS10713.1 CCDS CCDS42156.1 |
Transforming growth factor beta-1-induced transcript 1 protein is a protein that in humans is encoded by the TGFB1I1 gene. This gene encodes a coactivator of the androgen receptor, a transcription factor which is activated by androgen and has a key role in male sexual differentiation. The encoded protein is thought to regulate androgen receptor activity and may have a role to play in the treatment of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. May play a role in the processes of cell growth, proliferation, migration, differentiation and senescence. May have a zinc-dependent DNA-binding activity.
Products for TGFB1I1 gene
Catalog | Product Name | Application | Company |
GFS:E01585 | transforming growth factor beta 1 induced transcript 1; ELISA kit | ELISA | n/a |
GFS:A01585 | transforming growth factor beta 1 induced transcript 1; Anti | ANTIBODIES | n/a |
GFS:P01585 | transforming growth factor beta 1 induced transcript 1; Protien | Protien | n/a |