Symbol: Name: ID: |
TLR6 toll-like receptor 6 GFS:5808 |
Gene name: | TLR6 |
Chromosome: | 4p16.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CD286 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1341296 | Rat Genome Database ID: | RGD:1303030 |
HGNC ID: | HGNC:16711 | RefSeq IDs: | NM_006068 |
Entrez Gene ID: | 10333 | Ensembl Gene ID: | ENSG00000174130 |
VEGA IDs: | OTTHUMG00000128579 | UniProt ID: | Q9Y2C9 |
UCSC ID: | uc003gtm.2 | OMIM ID: | 605403 |
Pubmed: | PMID10231569 | ||
CCDS IDs: | CCDSCCDS3446.1 |
Toll-like receptor 6 is a protein that in humans is encoded by the TLR6 gene. TLR6 has also been designated as CD286 (cluster of differentiation 286).
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.[provided by RefSeq, Jan 2011]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for TLR6 gene
Catalog | Product Name | Application | Company |
GFS:E05808 | toll-like receptor 6; ELISA kit | ELISA | n/a |
GFS:A05808 | toll-like receptor 6; Anti | ANTIBODIES | n/a |
GFS:P05808 | toll-like receptor 6; Protien | Protien | n/a |