Symbol: Name: ID: |
SYN3 synapsin III GFS:1356 |
Gene name: | SYN3 |
Chromosome: | 22q12.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1351334 | Rat Genome Database ID: | RGD:3799 |
HGNC ID: | HGNC:11496 | RefSeq IDs: | NM_001135774 |
Entrez Gene ID: | 8224 | Ensembl Gene ID: | ENSG00000185666 |
VEGA IDs: | OTTHUMG00000031004 | UniProt ID: | O14994 |
UCSC ID: | uc003amx.2 | OMIM ID: | 602705 |
Pubmed: | PMID9539796 | ||
CCDS IDs: | CCDSCCDS13908.1 |
Synapsin-3 is a protein that in humans is encoded by the SYN3 gene. This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite direction. Alternative splicing of this gene results in multiple splice variants that encode different isoforms. [provided by RefSeq].
Function: May be involved in the regulation of neurotransmitter release and synaptogenesis.
Products for SYN3 gene
Catalog | Product Name | Application | Company |
GFS:E01356 | synapsin III; ELISA kit | ELISA | n/a |
GFS:A01356 | synapsin III; Anti | ANTIBODIES | n/a |
GFS:P01356 | synapsin III; Protien | Protien | n/a |