Symbol: Name: ID: |
SYNJ2 synaptojanin 2 GFS:1365 |
Gene name: | SYNJ2 |
Chromosome: | 6q25.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | INPP5H |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1201671 | Rat Genome Database ID: | RGD:69436 |
HGNC ID: | HGNC:11504 | RefSeq IDs: | NM_001178088 |
Entrez Gene ID: | 8871 | Ensembl Gene ID: | ENSG00000078269 |
VEGA IDs: | OTTHUMG00000015904 | UniProt ID: | O15056 |
UCSC ID: | uc003qqx.1 | OMIM ID: | 609410 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS5254.1 |
The SYNJ2 gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Inositol 5-phosphatase which may be involved in distinct membrane trafficking and signal transduction pathways. May mediate the inhibitory effect of Rac1 on endocytosis.
Products for SYNJ2 gene
Catalog | Product Name | Application | Company |
GFS:E01365 | synaptojanin 2; ELISA kit | ELISA | n/a |
GFS:A01365 | synaptojanin 2; Anti | ANTIBODIES | n/a |
GFS:P01365 | synaptojanin 2; Protien | Protien | n/a |