Symbol: Name: ID: |
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein GFS:6004 |
Gene name: | SYNCRIP |
Chromosome: | 6q14-q15 |
Previous Symbols: | |
Previous Names: | |
Aliases: | NSAP1, GRY-RBP, dJ3J17.2, HNRPQ1, hnRNP-Q |
Name Aliases: | heterogeneous nuclear ribonucleoprotein Q |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1891690 | Rat Genome Database ID: | RGD:1305683 |
HGNC ID: | HGNC:16918 | RefSeq IDs: | NM_001159673 |
Entrez Gene ID: | 10492 | Ensembl Gene ID: | ENSG00000135316 |
VEGA IDs: | OTTHUMG00000015141 | UniProt ID: | O60506 |
UCSC ID: | uc003pla.2 | OMIM ID: | |
Pubmed: | PMID9847309 PMID 11352648 | ||
CCDS IDs: | CCDSCCDS5005.1 |
Heterogeneous nuclear ribonucleoprotein Q is a protein that in humans is encoded by the SYNCRIP gene.
Function: Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. Component of the CRD-mediated complex that promotes MYC mRNA stability. Isoform 1, isoform 2 and isoform 3 are associated in vitro with pre-mRNA, splicing intermediates and mature mRNA protein complexes. Isoform 1 binds to apoB mRNA AU-rich sequences. Isoform 1 is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences. Isoform 3 may be involved in cytoplasmic vesicle-based mRNA transport through interaction with synaptotagmins.
Products for SYNCRIP gene
Catalog | Product Name | Application | Company |
GFS:E06004 | synaptotagmin binding, cytoplasmic RNA interacting protein; ELISA kit | ELISA | n/a |
GFS:A06004 | synaptotagmin binding, cytoplasmic RNA interacting protein; Anti | ANTIBODIES | n/a |
GFS:P06004 | synaptotagmin binding, cytoplasmic RNA interacting protein; Protien | Protien | n/a |