Symbol: Name: ID: |
SCN10A sodium channel, voltage-gated, type X, alpha subunit GFS:508 |
Gene name: | SCN10A |
Chromosome: | 3p22.2 |
Previous Symbols: | |
Previous Names: | sodium channel, voltage-gated, type X, alpha polypeptide |
Aliases: | Nav1.8, hPN3, SNS, PN3 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:108029 | Rat Genome Database ID: | RGD:3629 |
HGNC ID: | HGNC:10582 | RefSeq IDs: | NM_006514 |
Entrez Gene ID: | 6336 | Ensembl Gene ID: | ENSG00000185313 |
VEGA IDs: | OTTHUMG00000048245 | UniProt ID: | Q9Y5Y9 |
UCSC ID: | uc003ciq.2 | OMIM ID: | 604427 |
Pubmed: | PMID9839820 PMID 10198179 PMID 16382098 | ||
CCDS IDs: | CCDSCCDS33736.1 |
Voltage-gated sodium channels are integral membrane glycoproteins that are responsible for the initial rising phase of action in most excitable cells. They are composed of a large alpha subunit that may be associated with one or more smaller beta subunits. Sodium channels can be differentiated by their primary structure, kinetics, and relative sensitivity to the neurotoxin tetrodotoxin (TTX). Sodium channels, particularly those with TTX-resistant currents, have been found to accumulate in the region of peripheral nerve injury and may be important in chronic pain. SCN10A encodes a TTX-resistant channel that is restricted to the peripheral sensory nervous system (Rabert et al., 1998 [PubMed 9839820]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for SCN10A gene
Catalog | Product Name | Application | Company |
GFS:E00508 | sodium channel, voltage-gated, type X, alpha subunit; ELISA kit | ELISA | n/a |
GFS:A00508 | sodium channel, voltage-gated, type X, alpha subunit; Anti | ANTIBODIES | n/a |
GFS:P00508 | sodium channel, voltage-gated, type X, alpha subunit; Protien | Protien | n/a |