Symbol: Name: ID: |
SCN9A sodium channel, voltage-gated, type IX, alpha subunit GFS:521 |
Gene name: | SCN9A |
Chromosome: | 2q24 |
Previous Symbols: | |
Previous Names: | sodium channel, voltage-gated, type IX, alpha polypeptide |
Aliases: | Nav1.7, PN1, NE-NA, NENA, ETHA |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:107636 | Rat Genome Database ID: | RGD:69368 |
HGNC ID: | HGNC:10597 | RefSeq IDs: | NM_002977 |
Entrez Gene ID: | 6335 | Ensembl Gene ID: | ENSG00000169432 |
VEGA IDs: | OTTHUMG00000154044 | UniProt ID: | Q15858 |
UCSC ID: | uc010fpl.2 | OMIM ID: | 603415 |
Pubmed: | PMID7720699 PMID 10198179 PMID 16382098 | ||
CCDS IDs: | CCDSCCDS46441.1 |
SCN9A encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder. [provided by RefSeq]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na(+) channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain (By similarity)
Products for SCN9A gene
Catalog | Product Name | Application | Company |
GFS:E00521 | sodium channel, voltage-gated, type IX, alpha subunit; ELISA kit | ELISA | n/a |
GFS:A00521 | sodium channel, voltage-gated, type IX, alpha subunit; Anti | ANTIBODIES | n/a |
GFS:P00521 | sodium channel, voltage-gated, type IX, alpha subunit; Protien | Protien | n/a |