Symbol: Name: ID: |
SIRT1 sirtuin 1 GFS:4214 |
Gene name: | SIRT1 |
Chromosome: | 10q21 |
Previous Symbols: | |
Previous Names: | sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 1, "sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)" |
Aliases: | SIR2L1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2135607 | Rat Genome Database ID: | RGD:1308542 |
HGNC ID: | HGNC:14929 | RefSeq IDs: | NM_001142498 |
Entrez Gene ID: | 23411 | Ensembl Gene ID: | ENSG00000096717 |
VEGA IDs: | OTTHUMG00000018340 | UniProt ID: | Q96EB6 |
UCSC ID: | uc001jnd.2 | OMIM ID: | 604479 |
Pubmed: | PMID10381378 | ||
CCDS IDs: | CCDSCCDS7273.1 CCDS CCDS44412.1 |
Sirtuin 1, also known as NAD-dependent deacetylase sirtuin-1, is a protein that in humans is encoded by the SIRT1 gene.
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008].
Products for SIRT1 gene
Catalog | Product Name | Application | Company |
GFS:E04214 | sirtuin 1; ELISA kit | ELISA | n/a |
GFS:A04214 | sirtuin 1; Anti | ANTIBODIES | n/a |
GFS:P04214 | sirtuin 1; Protien | Protien | n/a |