Symbol: Name: ID: |
RGS8 regulator of G-protein signaling 8 GFS:5896 |
Gene name: | RGS8 |
Chromosome: | 1q25 |
Previous Symbols: | |
Previous Names: | regulator of G-protein signalling 8 |
Aliases: | MGC119067, MGC119068, MGC119069 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:108408 | Rat Genome Database ID: | RGD:3571 |
HGNC ID: | HGNC:16810 | RefSeq IDs: | NM_001102450 |
Entrez Gene ID: | 85397 | Ensembl Gene ID: | ENSG00000135824 |
VEGA IDs: | OTTHUMG00000035219 | UniProt ID: | P57771 |
UCSC ID: | uc001gpm.1 | OMIM ID: | 607189 |
Pubmed: | PMID11318611 | ||
CCDS IDs: | CCDSCCDS1349.1 CCDS CCDS41443.1 |
Regulator of G-protein signaling 8 is a protein that in humans is encoded by the RGS8 gene.
This gene is a member of the regulator of G protein signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation. [provided by RefSeq, Jul 2008].
Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Preferentially binds to G(o)-alpha and G(i)-alpha-3 (By similarity).
Products for RGS8 gene
Catalog | Product Name | Application | Company |
GFS:E05896 | regulator of G-protein signaling 8; ELISA kit | ELISA | n/a |
GFS:A05896 | regulator of G-protein signaling 8; Anti | ANTIBODIES | n/a |
GFS:P05896 | regulator of G-protein signaling 8; Protien | Protien | n/a |