Symbol: Name: ID: |
RGS20 regulator of G-protein signaling 20 GFS:3902 |
Gene name: | RGS20 |
Chromosome: | 8q11.23 |
Previous Symbols: | |
Previous Names: | regulator of G-protein signalling 20 |
Aliases: | RGSZ1, ZGAP1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1929866 | Rat Genome Database ID: | RGD:1586146 |
HGNC ID: | HGNC:14600 | RefSeq IDs: | NM_003702 |
Entrez Gene ID: | 8601 | Ensembl Gene ID: | ENSG00000147509 |
VEGA IDs: | UniProt ID: | O76081 | |
UCSC ID: | uc003xrp.2 | OMIM ID: | 607193 |
Pubmed: | PMID9748279 PMID 9748280 | ||
CCDS IDs: | CCDSCCDS6155.1 CCDS CCDS6156.1 |
Regulator of G-protein signaling 20 is a protein that in humans is encoded by the RGS20 gene.
The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds selectively to G(z)-alpha and G(alpha)-i2 subunits, accelerates their GTPase activity and regulates their signaling activities. The G(z)-alpha activity is inhibited by the phosphorylation and palmitoylation of the G-protein. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity).
Products for RGS20 gene
Catalog | Product Name | Application | Company |
GFS:E03902 | regulator of G-protein signaling 20; ELISA kit | ELISA | n/a |
GFS:A03902 | regulator of G-protein signaling 20; Anti | ANTIBODIES | n/a |
GFS:P03902 | regulator of G-protein signaling 20; Protien | Protien | n/a |