Symbol: Name: ID: |
RGS19 regulator of G-protein signaling 19 GFS:3242 |
Gene name: | RGS19 |
Chromosome: | 20q13.33 |
Previous Symbols: | |
Previous Names: | regulator of G-protein signalling 19 |
Aliases: | GAIP, RGSGAIP |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1915153 | Rat Genome Database ID: | RGD:629471 |
HGNC ID: | HGNC:13735 | RefSeq IDs: | NM_001039467 |
Entrez Gene ID: | 10287 | Ensembl Gene ID: | ENSG00000171700 |
VEGA IDs: | OTTHUMG00000033024 | UniProt ID: | P49795 |
UCSC ID: | uc002yib.2 | OMIM ID: | 605071 |
Pubmed: | PMID8524874 | ||
CCDS IDs: | CCDSCCDS13555.1 |
Regulator of G-protein signaling 19 is a protein that in humans is encoded by the RGS19 gene.
G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G-protein signaling) family and specifically interacts with G protein, GAI3. This protein is a guanosine triphosphatase-activating protein that functions to down-regulate Galpha i/Galpha q-linked signaling. Alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008].
Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
Products for RGS19 gene
Catalog | Product Name | Application | Company |
GFS:E03242 | regulator of G-protein signaling 19; ELISA kit | ELISA | n/a |
GFS:A03242 | regulator of G-protein signaling 19; Anti | ANTIBODIES | n/a |
GFS:P03242 | regulator of G-protein signaling 19; Protien | Protien | n/a |