Symbol: Name: ID: |
HDAC10 histone deacetylase 10 GFS:7017 |
Gene name: | HDAC10 |
Chromosome: | 22q13.31 |
Previous Symbols: | |
Previous Names: | |
Aliases: | DKFZP761B039 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2158340 | Rat Genome Database ID: | RGD:1305874 |
HGNC ID: | HGNC:18128 | RefSeq IDs: | NM_001159286 |
Entrez Gene ID: | 83933 | Ensembl Gene ID: | ENSG00000100429 |
VEGA IDs: | OTTHUMG00000044647 | UniProt ID: | Q969S8 |
UCSC ID: | uc003bkg.2 | OMIM ID: | 608544 |
Pubmed: | PMID11677242 PMID 11726666 | ||
CCDS IDs: | CCDSCCDS14088.1 |
Histone deacetylase 10 is an enzyme that in humans is encoded by the HDAC10 gene.
The protein encoded by this gene belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones. Histone deacetylation modulates chromatin structure, and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
Function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
Products for HDAC10 gene
Catalog | Product Name | Application | Company |
GFS:E07017 | histone deacetylase 10; ELISA kit | ELISA | n/a |
GFS:A07017 | histone deacetylase 10; Anti | ANTIBODIES | n/a |
GFS:P07017 | histone deacetylase 10; Protien | Protien | n/a |