Symbol: Name: ID: |
CHRNA6 cholinergic receptor, nicotinic, alpha 6 GFS:5095 |
Gene name: | CHRNA6 |
Chromosome: | 8p22 |
Previous Symbols: | |
Previous Names: | cholinergic receptor, nicotinic, alpha polypeptide 6 |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:106213 | Rat Genome Database ID: | RGD:69281 |
HGNC ID: | HGNC:15963 | RefSeq IDs: | NM_001199279 |
Entrez Gene ID: | 8973 | Ensembl Gene ID: | ENSG00000147434 |
VEGA IDs: | UniProt ID: | Q15825 | |
UCSC ID: | uc003xpj.2 | OMIM ID: | 606888 |
Pubmed: | PMID8906617 | ||
CCDS IDs: | CCDSCCDS6135.1 |
Cholinergic receptor, nicotinic, alpha 6, also known as CHRNA6, is a human gene.
This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence. [provided by RefSeq, Dec 2010].
Function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Products for CHRNA6 gene
Catalog | Product Name | Application | Company |
GFS:E05095 | cholinergic receptor, nicotinic, alpha 6; ELISA kit | ELISA | n/a |
GFS:A05095 | cholinergic receptor, nicotinic, alpha 6; Anti | ANTIBODIES | n/a |
GFS:P05095 | cholinergic receptor, nicotinic, alpha 6; Protien | Protien | n/a |