Symbol: Name: ID: |
CHRNA10 cholinergic receptor, nicotinic, alpha 10 GFS:3281 |
Gene name: | CHRNA10 |
Chromosome: | 11p15.5 |
Previous Symbols: | |
Previous Names: | cholinergic receptor, nicotinic, alpha polypeptide 10 |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:3609260 | Rat Genome Database ID: | RGD:620142 |
HGNC ID: | HGNC:13800 | RefSeq IDs: | NM_020402 |
Entrez Gene ID: | 57053 | Ensembl Gene ID: | ENSG00000129749 |
VEGA IDs: | OTTHUMG00000011844 | UniProt ID: | Q9GZZ6 |
UCSC ID: | uc001lyf.2 | OMIM ID: | 606372 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS7745.1 |
Function: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.
Products for CHRNA10 gene
Catalog | Product Name | Application | Company |
GFS:E03281 | cholinergic receptor, nicotinic, alpha 10; ELISA kit | ELISA | n/a |
GFS:A03281 | cholinergic receptor, nicotinic, alpha 10; Anti | ANTIBODIES | n/a |
GFS:P03281 | cholinergic receptor, nicotinic, alpha 10; Protien | Protien | n/a |