Symbol: Name: ID: |
CEL carboxyl ester lipase (bile salt-stimulated lipase) GFS:7327 |
Gene name: | CEL |
Chromosome: | 9q34.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | BSSL, MODY8 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:88374 | Rat Genome Database ID: | RGD:2331 |
HGNC ID: | HGNC:1848 | RefSeq IDs: | NM_001807 |
Entrez Gene ID: | 1056 | Ensembl Gene ID: | ENSG00000170835 |
VEGA IDs: | OTTHUMG00000020855 | UniProt ID: | P19835 |
UCSC ID: | uc010naa.1 | OMIM ID: | 114840 |
Pubmed: | PMID1676983 | ||
CCDS IDs: | CCDSCCDS43896.1 |
The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides.
Products for CEL gene
Catalog | Product Name | Application | Company |
GFS:E07327 | carboxyl ester lipase (bile salt-stimulated lipase); ELISA kit | ELISA | n/a |
GFS:A07327 | carboxyl ester lipase (bile salt-stimulated lipase); Anti | ANTIBODIES | n/a |
GFS:P07327 | carboxyl ester lipase (bile salt-stimulated lipase); Protien | Protien | n/a |