Symbol: Name: ID: |
CA1 carbonic anhydrase I GFS:3202 |
Gene name: | CA1 |
Chromosome: | 8q21.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | Car1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:88268 | Rat Genome Database ID: | RGD:1309780 |
HGNC ID: | HGNC:1368 | RefSeq IDs: | NM_001128829 |
Entrez Gene ID: | 759 | Ensembl Gene ID: | ENSG00000133742 |
VEGA IDs: | UniProt ID: | P00915 | |
UCSC ID: | uc010mae.1 | OMIM ID: | 114800 |
Pubmed: | PMID1916821 | ||
CCDS IDs: | CCDSCCDS6237.1 |
Carbonic anhydrase 1 is an enzyme that in humans is encoded by the CA1 gene.
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Variants of this gene have been described in some populations. Multiple alternatively spliced variants, encoding the same protein, have been identified. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature. [provided by RefSeq, Sep 2009].
Function: Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea.
Products for CA1 gene
Catalog | Product Name | Application | Company |
GFS:E03202 | carbonic anhydrase I; ELISA kit | ELISA | n/a |
GFS:A03202 | carbonic anhydrase I; Anti | ANTIBODIES | n/a |
GFS:P03202 | carbonic anhydrase I; Protien | Protien | n/a |