Symbol: Name: ID: |
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 GFS:1008 |
Gene name: | SMARCA4 |
Chromosome: | 19p13.3 |
Previous Symbols: | SNF2L4 |
Previous Names: | |
Aliases: | hSNF2b, BRG1, BAF190, SNF2, SWI2, SNF2-BETA, SNF2LB, FLJ39786 |
Name Aliases: | SNF2-like 4, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:88192 | Rat Genome Database ID: | RGD:621728 |
HGNC ID: | HGNC:11100 | RefSeq IDs: | NM_001128844 |
Entrez Gene ID: | 6597 | Ensembl Gene ID: | ENSG00000127616 |
VEGA IDs: | UniProt ID: | P51532 | |
UCSC ID: | uc002mqf.3 | OMIM ID: | 603254 |
Pubmed: | PMID8208605 | ||
CCDS IDs: | CCDSCCDS12253.1 CCDS CCDS45971.1 CCDS CCDS45972.1 CCDS CCDS45973.1 |
Transcription activator BRG1 also known as ATP-dependent helicase SMARCA4 is a protein that in humans is encoded by the SMARCA4 gene. The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Products for SMARCA4 gene
Catalog | Product Name | Application | Company |
GFS:E01008 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4; ELISA kit | ELISA | n/a |
GFS:A01008 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4; Anti | ANTIBODIES | n/a |
GFS:P01008 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4; Protien | Protien | n/a |