Symbol: Name: ID: |
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) GFS:721 |
Gene name: | SGCA |
Chromosome: | 17q21 |
Previous Symbols: | ADL |
Previous Names: | sarcoglycan, alpha (50kD dystrophin-associated glycoprotein) |
Aliases: | SCARMD1, LGMD2D, adhalin, DMDA2, A2 |
Name Aliases: | 50kD DAG, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:894698 | Rat Genome Database ID: | RGD:1308062 |
HGNC ID: | HGNC:10805 | RefSeq IDs: | NM_000023 |
Entrez Gene ID: | 6442 | Ensembl Gene ID: | ENSG00000108823 |
VEGA IDs: | UniProt ID: | Q16586 | |
UCSC ID: | uc002iqi.2 | OMIM ID: | 600119 |
Pubmed: | PMID7937874 | ||
CCDS IDs: | CCDSCCDS32679.1 CCDS CCDS45729.1 |
Alpha-sarcoglycan is a protein that in humans is encoded by the SGCA gene. This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Products for SGCA gene
Catalog | Product Name | Application | Company |
GFS:E00721 | sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein); ELISA kit | ELISA | n/a |
GFS:A00721 | sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein); Anti | ANTIBODIES | n/a |
GFS:P00721 | sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein); Protien | Protien | n/a |