Symbol: Name: ID: |
CAPN9 calpain 9 GFS:4147 |
Gene name: | CAPN9 |
Chromosome: | 1q42.11-q42.3 |
Previous Symbols: | |
Previous Names: | calpain 9 (nCL-4) |
Aliases: | nCL-4, GC36 |
Name Aliases: | novel calpain large subunit-4 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1920897 | Rat Genome Database ID: | RGD:70965 |
HGNC ID: | HGNC:1486 | RefSeq IDs: | NM_006615 |
Entrez Gene ID: | 10753 | Ensembl Gene ID: | ENSG00000135773 |
VEGA IDs: | OTTHUMG00000037779 | UniProt ID: | O14815 |
UCSC ID: | uc001htz.1 | OMIM ID: | 606401 |
Pubmed: | PMID9524069 PMID 10835488 | ||
CCDS IDs: | CCDSCCDS1586.1 CCDS CCDS31053.1 |
Calpain-9 is a protein that in humans is encoded by the CAPN9 gene.
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Function: Calcium-regulated non-lysosomal thiol-protease (By similarity).
Products for CAPN9 gene
Catalog | Product Name | Application | Company |
GFS:E04147 | calpain 9; ELISA kit | ELISA | n/a |
GFS:A04147 | calpain 9; Anti | ANTIBODIES | n/a |
GFS:P04147 | calpain 9; Protien | Protien | n/a |