Symbol: Name: ID: |
CAPNS1 calpain, small subunit 1 GFS:4094 |
Gene name: | CAPNS1 |
Chromosome: | 19q13.1 |
Previous Symbols: | CAPN4 |
Previous Names: | |
Aliases: | CANP, CANPS, 30K, CDPS |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:88266 | Rat Genome Database ID: | RGD:2270 |
HGNC ID: | HGNC:1481 | RefSeq IDs: | NM_001003962 |
Entrez Gene ID: | 826 | Ensembl Gene ID: | ENSG00000126247 |
VEGA IDs: | UniProt ID: | P04632 | |
UCSC ID: | uc002odk.2 | OMIM ID: | 114170 |
Pubmed: | PMID3024120 PMID 3016651 | ||
CCDS IDs: | CCDSCCDS12489.1 |
Calpain small subunit 1 is a protein that in humans is encoded by the CAPNS1 gene.
Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].
Function: Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
Products for CAPNS1 gene
Catalog | Product Name | Application | Company |
GFS:E04094 | calpain, small subunit 1; ELISA kit | ELISA | n/a |
GFS:A04094 | calpain, small subunit 1; Anti | ANTIBODIES | n/a |
GFS:P04094 | calpain, small subunit 1; Protien | Protien | n/a |