Symbol: Name: ID: |
CAPN3 calpain 3, (p94) GFS:4084 |
Gene name: | CAPN3 |
Chromosome: | 15q15.1 |
Previous Symbols: | LGMD2, LGMD2A |
Previous Names: | |
Aliases: | CANP3, p94, nCL-1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:107437 | Rat Genome Database ID: | RGD:2269 |
HGNC ID: | HGNC:1480 | RefSeq IDs: | NM_000070 |
Entrez Gene ID: | 825 | Ensembl Gene ID: | ENSG00000092529 |
VEGA IDs: | OTTHUMG00000130619 | UniProt ID: | P20807 |
UCSC ID: | uc001zpo.1 | OMIM ID: | 114240 |
Pubmed: | PMID2555341 PMID 7720071 | ||
CCDS IDs: | CCDSCCDS10085.1 CCDS CCDS10086.1 CCDS CCDS32207.1 CCDS CCDS42027.1 CCDS CCDS45245.1 CCDS CCDS45246.1 |
Calpain-3 is a protein that in humans is encoded by the CAPN3 gene.
Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed. [provided by RefSeq, Jul 2008].
Function: Calcium-regulated non-lysosomal thiol-protease.
Products for CAPN3 gene
Catalog | Product Name | Application | Company |
GFS:E04084 | calpain 3, (p94); ELISA kit | ELISA | n/a |
GFS:A04084 | calpain 3, (p94); Anti | ANTIBODIES | n/a |
GFS:P04084 | calpain 3, (p94); Protien | Protien | n/a |