Symbol: Name: ID: |
ACO2 aconitase 2, mitochondrial GFS:1614 |
Gene name: | ACO2 |
Chromosome: | 22q13.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | ACONM |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:87880 | Rat Genome Database ID: | RGD:621360 |
HGNC ID: | HGNC:118 | RefSeq IDs: | NM_001098 |
Entrez Gene ID: | Ensembl Gene ID: | ENSG00000100412 | |
VEGA IDs: | OTTHUMG00000030544 | UniProt ID: | Q99798 |
UCSC ID: | uc003bac.2 | OMIM ID: | 100850 |
Pubmed: | PMID10591208 | ||
CCDS IDs: | CCDSCCDS14017.1 |
The protein encoded by ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (By similarity).
Products for ACO2 gene
Catalog | Product Name | Application | Company |
GFS:E01614 | aconitase 2, mitochondrial; ELISA kit | ELISA | n/a |
GFS:A01614 | aconitase 2, mitochondrial; Anti | ANTIBODIES | n/a |
GFS:P01614 | aconitase 2, mitochondrial; Protien | Protien | n/a |