Symbol: Name: ID: |
UGT8 UDP glycosyltransferase 8 GFS:2344 |
Gene name: | UGT8 |
Chromosome: | 4q26 |
Previous Symbols: | CGT |
Previous Names: | UDP-galactose ceramide galactosyltransferase |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:109522 | Rat Genome Database ID: | RGD:3938 |
HGNC ID: | HGNC:12555 | RefSeq IDs: | NM_001128174 |
Entrez Gene ID: | 7368 | Ensembl Gene ID: | ENSG00000174607 |
VEGA IDs: | OTTHUMG00000132915 | UniProt ID: | Q16880 |
UCSC ID: | uc003ibs.2 | OMIM ID: | 601291 |
Pubmed: | PMID8661025 | ||
CCDS IDs: | CCDSCCDS3705.1 |
2-hydroxyacylsphingosine 1-beta-galactosyltransferase is an enzyme that in humans is encoded by the UGT8 gene.
Galactocerebrosides are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system and are also present in small amounts in kidney. The key enzymatic step in the biosynthesis of galactocerebrosides consists of the transfer of galactose to ceramide catalyzed by UDP-galactose ceramide galactosyltransferase (CGT, EC 2.4.1.45). The enzyme encoded by the CGT gene is the first involved in complex lipid biosynthesis in the myelinating oligodendrocyte.[supplied by OMIM].
Function: Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system.
Products for UGT8 gene
Catalog | Product Name | Application | Company |
GFS:E02344 | UDP glycosyltransferase 8; ELISA kit | ELISA | n/a |
GFS:A02344 | UDP glycosyltransferase 8; Anti | ANTIBODIES | n/a |
GFS:P02344 | UDP glycosyltransferase 8; Protien | Protien | n/a |