Symbol: Name: ID: |
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 GFS:2330 |
Gene name: | UGT1A9 |
Chromosome: | 2q37 |
Previous Symbols: | |
Previous Names: | UDP glycosyltransferase 1 family, polypeptide A9 |
Aliases: | HLUGP4, LUGP4, UGT1AI |
Name Aliases: | |
Locus Type: | complex locus constituent |
Mouse Genome Database ID: | MGI:3576092 | Rat Genome Database ID: | RGD:1549771 |
HGNC ID: | HGNC:12541 | RefSeq IDs: | NM_021027 |
Entrez Gene ID: | 54600 | Ensembl Gene ID: | ENSG00000241119 |
VEGA IDs: | OTTHUMG00000059124 | UniProt ID: | O60656 |
UCSC ID: | OMIM ID: | 606434 | |
Pubmed: | PMID9295054 PMID 1910331 | ||
CCDS IDs: | CCDSCCDS2505.1 |
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols. (provided by RefSeq) .
Function: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols.
Products for UGT1A9 gene
Catalog | Product Name | Application | Company |
GFS:E02330 | UDP glucuronosyltransferase 1 family, polypeptide A9; ELISA kit | ELISA | n/a |
GFS:A02330 | UDP glucuronosyltransferase 1 family, polypeptide A9; Anti | ANTIBODIES | n/a |
GFS:P02330 | UDP glucuronosyltransferase 1 family, polypeptide A9; Protien | Protien | n/a |