Symbol: Name: ID: |
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 GFS:2335 |
Gene name: | UGT2B17 |
Chromosome: | 4q13 |
Previous Symbols: | |
Previous Names: | UDP glycosyltransferase 2 family, polypeptide B17 |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2140794 | Rat Genome Database ID: | RGD:628623 |
HGNC ID: | HGNC:12547 | RefSeq IDs: | NM_001077 |
Entrez Gene ID: | 7367 | Ensembl Gene ID: | ENSG00000197888 |
VEGA IDs: | OTTHUMG00000129305 | UniProt ID: | O75795 |
UCSC ID: | OMIM ID: | 601903 | |
Pubmed: | PMID8798464 | ||
CCDS IDs: | CCDSCCDS3523.1 |
UDP-glucuronosyltransferase 2B17 is an enzyme that in humans is encoded by the UGT2B17 gene.
This gene encodes a member of the uridine diphosphoglucuronosyltransferase protein family. The encoded enzyme catalyzes the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a diverse array of substrates including steroid hormones and lipid-soluble drugs. This process, known as glucuronidation, is an intermediate step in the metabolism of steroids. Copy number variation in this gene is associated with susceptibility to osteoporosis.
Function: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. The major substrates of this isozyme are eugenol > 4-methylumbelliferone > dihydrotestosterone (DHT) > androstane-3-alpha,17-beta-diol (3-alpha-diol) > testosterone > androsterone (ADT).
Products for UGT2B17 gene
Catalog | Product Name | Application | Company |
GFS:E02335 | UDP glucuronosyltransferase 2 family, polypeptide B17; ELISA kit | ELISA | n/a |
GFS:A02335 | UDP glucuronosyltransferase 2 family, polypeptide B17; Anti | ANTIBODIES | n/a |
GFS:P02335 | UDP glucuronosyltransferase 2 family, polypeptide B17; Protien | Protien | n/a |