Symbol: Name: ID: |
SOX8 SRY (sex determining region Y)-box 8 GFS:1104 |
Gene name: | SOX8 |
Chromosome: | 16p13.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98370 | Rat Genome Database ID: | RGD:1309072 |
HGNC ID: | HGNC:11203 | RefSeq IDs: | NM_014587 |
Entrez Gene ID: | 30812 | Ensembl Gene ID: | ENSG00000005513 |
VEGA IDs: | OTTHUMG00000122101 | UniProt ID: | P57073 |
UCSC ID: | uc002ckn.2 | OMIM ID: | 605923 |
Pubmed: | PMID10662550 PMID 10684944 | ||
CCDS IDs: | CCDSCCDS10428.1 |
Transcription factor SOX-8 is a protein that in humans is encoded by the SOX8 gene. This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome). [provided by RefSeq]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3' (By similarity).
Products for SOX8 gene
Catalog | Product Name | Application | Company |
GFS:E01104 | SRY (sex determining region Y)-box 8; ELISA kit | ELISA | n/a |
GFS:A01104 | SRY (sex determining region Y)-box 8; Anti | ANTIBODIES | n/a |
GFS:P01104 | SRY (sex determining region Y)-box 8; Protien | Protien | n/a |