Symbol: Name: ID: |
SOX4 SRY (sex determining region Y)-box 4 GFS:1101 |
Gene name: | SOX4 |
Chromosome: | 6p22.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98366 | Rat Genome Database ID: | RGD:1309488 |
HGNC ID: | HGNC:11200 | RefSeq IDs: | NM_003107 |
Entrez Gene ID: | 6659 | Ensembl Gene ID: | ENSG00000124766 |
VEGA IDs: | OTTHUMG00000016101 | UniProt ID: | Q06945 |
UCSC ID: | uc003ndi.2 | OMIM ID: | 184430 |
Pubmed: | PMID8268656 PMID 9730625 | ||
CCDS IDs: | CCDSCCDS4547.1 |
Transcription factor SOX-4 is a protein that in humans is encoded by the SOX4 gene. This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif.
Products for SOX4 gene
Catalog | Product Name | Application | Company |
GFS:E01101 | SRY (sex determining region Y)-box 4; ELISA kit | ELISA | n/a |
GFS:A01101 | SRY (sex determining region Y)-box 4; Anti | ANTIBODIES | n/a |
GFS:P01101 | SRY (sex determining region Y)-box 4; Protien | Protien | n/a |