Symbol: Name: ID: |
SOX6 SRY (sex determining region Y)-box 6 GFS:5534 |
Gene name: | SOX6 |
Chromosome: | 11p15.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98368 | Rat Genome Database ID: | RGD:1309000 |
HGNC ID: | HGNC:16421 | RefSeq IDs: | NM_001145811 |
Entrez Gene ID: | 55553 | Ensembl Gene ID: | ENSG00000110693 |
VEGA IDs: | UniProt ID: | P35712 | |
UCSC ID: | uc001mme.2 | OMIM ID: | 607257 |
Pubmed: | PMID11255018 | ||
CCDS IDs: | CCDSCCDS7821.1 |
Transcription factor SOX-6 is a protein that in humans is encoded by the SOX6 gene.
This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009].
Function: Transcriptional activator. Binds specifically to the DNA sequence 5'-AACAAT-3'. Plays a key role in several developmental processes, including neurogenesis and skeleton formation.
Products for SOX6 gene
Catalog | Product Name | Application | Company |
GFS:E05534 | SRY (sex determining region Y)-box 6; ELISA kit | ELISA | n/a |
GFS:A05534 | SRY (sex determining region Y)-box 6; Anti | ANTIBODIES | n/a |
GFS:P05534 | SRY (sex determining region Y)-box 6; Protien | Protien | n/a |