Symbol: Name: ID: |
SOX17 SRY (sex determining region Y)-box 17 GFS:7011 |
Gene name: | SOX17 |
Chromosome: | 8q11.23 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:107543 | Rat Genome Database ID: | RGD:1305371 |
HGNC ID: | HGNC:18122 | RefSeq IDs: | NM_022454 |
Entrez Gene ID: | 64321 | Ensembl Gene ID: | ENSG00000164736 |
VEGA IDs: | UniProt ID: | Q9H6I2 | |
UCSC ID: | uc003xsb.3 | OMIM ID: | 610928 |
Pubmed: | PMID11786926 | ||
CCDS IDs: | CCDSCCDS6159.1 |
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells (By similarity).
Products for SOX17 gene
Catalog | Product Name | Application | Company |
GFS:E07011 | SRY (sex determining region Y)-box 17; ELISA kit | ELISA | n/a |
GFS:A07011 | SRY (sex determining region Y)-box 17; Anti | ANTIBODIES | n/a |
GFS:P07011 | SRY (sex determining region Y)-box 17; Protien | Protien | n/a |