| Symbol: Name: ID: |
FBXL8 F-box and leucine-rich repeat protein 8 GFS:6777 |
| Gene name: | FBXL8 |
| Chromosome: | 16q22.1-q22.3 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | Fbl8 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1354697 | Rat Genome Database ID: | RGD:1566420 |
| HGNC ID: | HGNC:17875 | RefSeq IDs: | NM_018378 |
| Entrez Gene ID: | 55336 | Ensembl Gene ID: | ENSG00000135722 |
| VEGA IDs: | OTTHUMG00000137514 | UniProt ID: | Q96CD0 |
| UCSC ID: | uc002erk.1 | OMIM ID: | 609077 |
| Pubmed: | |||
| CCDS IDs: | CCDSCCDS10831.1 | ||
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. It shares 78% sequence identity with the mouse protein. [provided by RefSeq, Jul 2008].
Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex (By similarity).
Products for FBXL8 gene
| Catalog | Product Name | Application | Company |
| GFS:E06777 | F-box and leucine-rich repeat protein 8; ELISA kit | ELISA | n/a |
| GFS:A06777 | F-box and leucine-rich repeat protein 8; Anti | ANTIBODIES | n/a |
| GFS:P06777 | F-box and leucine-rich repeat protein 8; Protien | Protien | n/a |
