Symbol: Name: ID: |
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) GFS:2878 |
Gene name: | BCL11B |
Chromosome: | 14q32 |
Previous Symbols: | ZNF856B |
Previous Names: | |
Aliases: | CTIP-2, CTIP2, hRIT1-alpha |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1929913 | Rat Genome Database ID: | RGD:1311128 |
HGNC ID: | HGNC:13222 | RefSeq IDs: | NM_022898 |
Entrez Gene ID: | 64919 | Ensembl Gene ID: | ENSG00000127152 |
VEGA IDs: | OTTHUMG00000028967 | UniProt ID: | Q9C0K0 |
UCSC ID: | uc001yga.2 | OMIM ID: | 606558 |
Pubmed: | PMID11719382 PMID 16950772 | ||
CCDS IDs: | CCDSCCDS9949.1 CCDS CCDS9950.1 |
B-cell lymphoma/leukemia 11B is a protein that in humans is encoded by the BCL11B gene.
This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. [provided by RefSeq].
Function: Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element (By similarity).
Products for BCL11B gene
Catalog | Product Name | Application | Company |
GFS:E02878 | B-cell CLL/lymphoma 11B (zinc finger protein); ELISA kit | ELISA | n/a |
GFS:A02878 | B-cell CLL/lymphoma 11B (zinc finger protein); Anti | ANTIBODIES | n/a |
GFS:P02878 | B-cell CLL/lymphoma 11B (zinc finger protein); Protien | Protien | n/a |