Symbol: Name: ID: |
ADAM12 ADAM metallopeptidase domain 12 GFS:7802 |
Gene name: | ADAM12 |
Chromosome: | 10q26 |
Previous Symbols: | |
Previous Names: | a disintegrin and metalloproteinase domain 12 (meltrin alpha) |
Aliases: | MCMPMltna, MLTN |
Name Aliases: | meltrin alpha |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:105378 | Rat Genome Database ID: | RGD:1583652 |
HGNC ID: | HGNC:190 | RefSeq IDs: | NM_003474 |
Entrez Gene ID: | 8038 | Ensembl Gene ID: | ENSG00000148848 |
VEGA IDs: | OTTHUMG00000019243 | UniProt ID: | O43184 |
UCSC ID: | uc001ljk.2 | OMIM ID: | 602714 |
Pubmed: | PMID9417060 PMID 18342566 | ||
CCDS IDs: | CCDSCCDS7653.1 CCDS CCDS7654.1 |
Disintegrin and metalloproteinase domain-containing protein 12 is an enzyme that in humans is encoded by the ADAM12 gene.
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis. [provided by RefSeq, Jul 2008].
Function: Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors (By similarity).
Products for ADAM12 gene
Catalog | Product Name | Application | Company |
GFS:E07802 | ADAM metallopeptidase domain 12; ELISA kit | ELISA | n/a |
GFS:A07802 | ADAM metallopeptidase domain 12; Anti | ANTIBODIES | n/a |
GFS:P07802 | ADAM metallopeptidase domain 12; Protien | Protien | n/a |