Symbol: Name: ID: |
ADAM11 ADAM metallopeptidase domain 11 GFS:7714 |
Gene name: | ADAM11 |
Chromosome: | 17q21.3 |
Previous Symbols: | MDC |
Previous Names: | a disintegrin and metalloproteinase domain 11 |
Aliases: | |
Name Aliases: | metalloproteinase-like, disintegrin-like, cysteine-rich protein |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1098667 | Rat Genome Database ID: | RGD:1307515 |
HGNC ID: | HGNC:189 | RefSeq IDs: | NM_002390 |
Entrez Gene ID: | 4185 | Ensembl Gene ID: | ENSG00000073670 |
VEGA IDs: | UniProt ID: | O75078 | |
UCSC ID: | uc002ihh.2 | OMIM ID: | 155120 |
Pubmed: | PMID8252040 | ||
CCDS IDs: | CCDSCCDS11486.1 |
Disintegrin and metalloproteinase domain-containing protein 11 is an enzyme that in humans is encoded by the ADAM11 gene.
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. [provided by RefSeq, Jul 2008].
Function: Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein.
Products for ADAM11 gene
Catalog | Product Name | Application | Company |
GFS:E07714 | ADAM metallopeptidase domain 11; ELISA kit | ELISA | n/a |
GFS:A07714 | ADAM metallopeptidase domain 11; Anti | ANTIBODIES | n/a |
GFS:P07714 | ADAM metallopeptidase domain 11; Protien | Protien | n/a |