Symbol: Name: ID: |
ZFP57 zinc finger protein 57 homolog (mouse) GFS:7615 |
Gene name: | ZFP57 |
Chromosome: | 6p22.1 |
Previous Symbols: | C6orf40 |
Previous Names: | chromosome 6 open reading frame 40 |
Aliases: | ZNF698, bA145L22, bA145L22.2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:99204 | Rat Genome Database ID: | RGD:1302981 |
HGNC ID: | HGNC:18791 | RefSeq IDs: | NM_001109809 |
Entrez Gene ID: | 346171 | Ensembl Gene ID: | |
VEGA IDs: | OTTHUMG00000031158 | UniProt ID: | Q9NU63 |
UCSC ID: | uc011dlw.1 | OMIM ID: | 612192 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS43436.1 |
The protein encoded by this gene is a zinc finger protein containing a KRAB domain. Studies in mouse suggest that this protein may function as a transcriptional repressor. Mutations in this gene have been associated with transient neonatal diabetes mellitus type 1 (TNDM1).[provided by RefSeq, Sep 2009].
Function: Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions. Required for the establishment of maternal methylation imprints at SNRPN locus. Acts as a transcriptional repressor in Schwann cells.
Products for ZFP57 gene
Catalog | Product Name | Application | Company |
GFS:E07615 | zinc finger protein 57 homolog (mouse); ELISA kit | ELISA | n/a |
GFS:A07615 | zinc finger protein 57 homolog (mouse); Anti | ANTIBODIES | n/a |
GFS:P07615 | zinc finger protein 57 homolog (mouse); Protien | Protien | n/a |