| Symbol: Name: ID: |
ZFP36 zinc finger protein 36, C3H type, homolog (mouse) GFS:2610 |
| Gene name: | ZFP36 |
| Chromosome: | 19q13.1 |
| Previous Symbols: | |
| Previous Names: | zinc finger protein, C3H type, 36 homolog (mouse) |
| Aliases: | RNF162A, TIS11, G0S24, TTP, NUP475 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:99180 | Rat Genome Database ID: | RGD:620722 |
| HGNC ID: | HGNC:12862 | RefSeq IDs: | NM_003407 |
| Entrez Gene ID: | 7538 | Ensembl Gene ID: | ENSG00000128016 |
| VEGA IDs: | UniProt ID: | P26651 | |
| UCSC ID: | uc002olh.1 | OMIM ID: | 190700 |
| Pubmed: | PMID1699942 | ||
| CCDS IDs: | CCDSCCDS12534.1 | ||
Tristetraprolin (TTP) also known as zinc finger protein 36 homolog (ZFP36) is a protein that in humans is encoded by the ZFP36 gene.
TTP binds to AU-rich elements (AREs) in the 3'-untranslated regions (UTRs) of the mRNAs of some cytokines and promotes their degradation. TTP is a component of a negative feedback loop that interferes with TNF-alpha production by destabilizing its mRNA. Mice deficient in TTP develop a complex syndrome of inflammatory diseases.
Function:Probable regulatory protein with a novel zinc finger structure involved in regulating the response to growth factors. Has been experimentally shown to be able to bind zinc.
Products for ZFP36 gene
| Catalog | Product Name | Application | Company |
| GFS:E02610 | zinc finger protein 36, C3H type, homolog (mouse); ELISA kit | ELISA | n/a |
| GFS:A02610 | zinc finger protein 36, C3H type, homolog (mouse); Anti | ANTIBODIES | n/a |
| GFS:P02610 | zinc finger protein 36, C3H type, homolog (mouse); Protien | Protien | n/a |
