Symbol: Name: ID: |
ZBTB16 zinc finger and BTB domain containing 16 GFS:2655 |
Gene name: | ZBTB16 |
Chromosome: | 11q23 |
Previous Symbols: | ZNF145 |
Previous Names: | zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia) |
Aliases: | PLZF |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:103222 | Rat Genome Database ID: | RGD:727921 |
HGNC ID: | HGNC:12930 | RefSeq IDs: | NM_001018011 |
Entrez Gene ID: | 7704 | Ensembl Gene ID: | ENSG00000109906 |
VEGA IDs: | UniProt ID: | Q05516 | |
UCSC ID: | uc001poq.2 | OMIM ID: | 176797 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS8367.1 |
Zinc finger and BTB domain-containing protein 16 is a protein that in humans is encoded by the ZBTB16 gene.
This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. [provided by RefSeq].
Function: Probable transcription factor. May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Products for ZBTB16 gene
Catalog | Product Name | Application | Company |
GFS:E02655 | zinc finger and BTB domain containing 16; ELISA kit | ELISA | n/a |
GFS:A02655 | zinc finger and BTB domain containing 16; Anti | ANTIBODIES | n/a |
GFS:P02655 | zinc finger and BTB domain containing 16; Protien | Protien | n/a |