Symbol: Name: ID: |
WNT6 wingless-type MMTV integration site family, member 6 GFS:2543 |
Gene name: | WNT6 |
Chromosome: | 2q35 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98960 | Rat Genome Database ID: | RGD:1304559 |
HGNC ID: | HGNC:12785 | RefSeq IDs: | NM_006522 |
Entrez Gene ID: | 7475 | Ensembl Gene ID: | ENSG00000115596 |
VEGA IDs: | OTTHUMG00000133082 | UniProt ID: | Q9Y6F9 |
UCSC ID: | uc002vjc.1 | OMIM ID: | 604663 |
Pubmed: | PMID10343101 PMID 11350055 | ||
CCDS IDs: | CCDSCCDS2425.1 |
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
Products for WNT6 gene
Catalog | Product Name | Application | Company |
GFS:E02543 | wingless-type MMTV integration site family, member 6; ELISA kit | ELISA | n/a |
GFS:A02543 | wingless-type MMTV integration site family, member 6; Anti | ANTIBODIES | n/a |
GFS:P02543 | wingless-type MMTV integration site family, member 6; Protien | Protien | n/a |