Symbol: Name: ID: |
WNT10A wingless-type MMTV integration site family, member 10A GFS:3304 |
Gene name: | WNT10A |
Chromosome: | 2q35 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:108071 | Rat Genome Database ID: | RGD:1307015 |
HGNC ID: | HGNC:13829 | RefSeq IDs: | NM_025216 |
Entrez Gene ID: | 80326 | Ensembl Gene ID: | ENSG00000135925 |
VEGA IDs: | OTTHUMG00000133085 | UniProt ID: | Q9GZT5 |
UCSC ID: | uc002vjd.1 | OMIM ID: | 606268 |
Pubmed: | PMID11350055 PMID 17847007 | ||
CCDS IDs: | CCDSCCDS2426.1 |
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters.
Products for WNT10A gene
Catalog | Product Name | Application | Company |
GFS:E03304 | wingless-type MMTV integration site family, member 10A; ELISA kit | ELISA | n/a |
GFS:A03304 | wingless-type MMTV integration site family, member 10A; Anti | ANTIBODIES | n/a |
GFS:P03304 | wingless-type MMTV integration site family, member 10A; Protien | Protien | n/a |